Friedel–crafts acylation: synthesis of 4-methoxyacetophenone prepared by jerry manion, university of central arkansas purpose synthesize 4-methoxyacetophenone by the friedel–crafts acylation of anisole with acetic anhydride characterize the product using infrared spectroscopy and nuclear magnetic resonance spectroscopy. Friedel-crafts acylation synthesis of 4-methoxyacetophenone click here to continue essay on a person who influenced my life joni edelman, a mother of five, released a controversial but beautiful personal essay about her experience with her weight in fact, the.
Friedel-crafts acylation of anisole with acetic anhydride was used in this experiement to synthesize 4-methoxyacetophenone with the use of a reflux apparatus friedel-crafts reactions can be done by alkylation, which involves mixing an alkyl or acyl halide with a lewis acid, or acylation, which is done with acid chlorides or anhydrides(lefevre.
Friedel crafts acylation synthesis of 4 methoxyacetophenone essays and research papers friedel crafts acylation synthesis of 4 methoxyacetophenone introduction friedel - crafts acylation of anisole with acetic anhydride was used in this experiement to synthesize 4 - methoxyacetophenone with the use of a reflux apparatus. Does friedel-crafts acylation of anisole produce ortho, meta, or para methoxyacetophenone, or a mixture of the three isomers acetic anhydride will be the acylating agent and dichloromethane will be the reaction solvent.
Acetate : hexanes = 1 : 4) in comparison with the proposed starting material these volumes are designed for the use of a 100-ml, round-bottomed (rb) flask if using a 250-ml rb flask, double and if using a 500-ml, rb flask, multiply by four notes: do not wash your glassware just before doing this experiment your glassware must be clean and dry. Friedel – crafts acylation: synthesis of 4-methoxyacetophenone 843 words | 4 pages introduction friedel-crafts acylation of anisole with acetic anhydride was used in this experiement to synthesize 4-methoxyacetophenone with the use of a reflux apparatus.
Acylation reactions require molar amounts of a lewis catalyst, in our case aluminum chloride (alcl 3) was used (arata, nakamura, & shouji) materials and methods reflux apparatus assembly using a condenser, claisen adapter, and a 25 ml round-bottom flask, a reflux apparatus was assembled. 10, 2010 lab: chem2212 w 3:30-6:30 title: the friedel-crafts alkylation reaction synthesis of 1,4-di-t-butyl-2,5-dimethoxybenzene with 1,4-dimethoxybenzene and t-butyl alcohol and sulfuric acid introduction: a friedel-crafts reaction is a type of electrophilic aromatic substitution reaction that consists of the introduction of an alkyl group onto the benzene ring, otherwise known as alkylation. Friedel-crafts acylation: synthesis of 4-methoxyacetophenone ashlee n chavez organic chemistry 2103 -08 january 27, 2013 abstract: the purpose of this lab was to use the friedel-crafts acylations of anisole with acetic anhydride to synthesize 4-methoxyacetophenone.